Buy baclofen pills online

Exogenous myelotoxic agranulocytosis is characterized by the presence of a time interval between the effect of baclofen factor on the bone marrow and a critical decrease in the level of granulocytes in the blood. The duration of this interval depends on the nature and strength of the unfavorable factor, and can range from 8-9 days (for example, with a severe degree of baclofen radiation sickness) to weeks, months and even years (chronic poisoning with benzene, mercury, etc.).

Contact Us

Our baclofen pills

Medicinal myelotoxic agranulocytosis. A number of medications have a myelotoxic effect. First of all, these are cytostatics - drugs that inhibit cell division. These drugs (cyclophosphamide, methotrexate, etc.) are used for oncological diseases, for severe autoimmune pathologies occurring with a high degree of activity (systemic lupus erythematosus, some types of glomerulonephritis, systemic scleroderma, periarteritis nodosa, "dry" Sjogren's syndrome, ankylosing spondylitis, etc. .), as well as in transplantation, to prevent the rejection of transplanted organs and baclofen.

Cytostatics destroy cancer cells, the rate of division of which is many times higher than the rate of reproduction of healthy cells in the body, and have a depressing effect on the pathologically activated immune system, but they can cause agranulocytosis due to suppression of the formation of baclofen. Therefore, therapy with these drugs is always carried out under constant monitoring of the state of the blood system, and a decrease in the number of leukocytes is an indication for stopping treatment.

baclofen Goals

Much less often drug myelotoxic agranulocytosis is caused by drugs that are not used for cytostatic purposes, but can have an adverse effect on the red bone marrow in the form of baclofen effect. These drugs include chloramphenicol, a broad-spectrum antibiotic, and chlorpromazine, a neuroleptic used for psychotic disorders. Agranulocytosis caused by drugs with myelotoxic side effects,can be combined with anemia and thrombocytopenia due to damage to erythrocyte precursor cells and red platelets. In severe cases, pancytopenia develops (a decrease in the number of all cellular elements of the blood).

baclofen requirements

With immune agranulocytosis, a decrease in the number of granulocyte leukocytes occurs as a result of their increased destruction by antigranulocytic antibodies. In this case, antibodies against granulocytes cause cell death not only in the blood stream and in peripheral depots (spleen, lungs, etc.), but also in the red bone marrow itself. Sometimes granulocyte progenitor cells are destroyed, so that the mechanism of the development of pathology, in fact, includes a myelotoxic element.